4-P-PDOT
4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist. 4-P-PDOT is >300-fold more selective for MT2 than MT1. 4-P-PDOT significantly counteracts Melatonin-mediated antioxidant effects (GSH/GSSG ratio, phospho-ERK, Nrf2 nuclear translocation, Nrf2 DNA-binding activity).
Catalog Number | E7113 |
Molecular Formula | C20H32F2O5 |
CAS# | 134865-74-0 |
Inchi | InChI=1S/C20H32F2O5/c1-2-3-12-20(21,22)18(25)11-10-15-14(16(23)13-17(15)24)8-6-4-5-7-9-19(26)27/h14-15,17,24H,2-13H2,1H3,(H,26,27)/t14-,15-,17-/m1/s1 |
Inchi Key | DBVFKLAGQHYVGQ-BFYDXBDKSA-N |
SMILES | CCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/4-p-pdot.html |
Additional Information | https://file.selleck.cn/downloads/struct/e7113-4-p-pdot-chemical-structure-tube.png |