GSK’872
GSK’872 is a potent and selective RIP3 kinase inhibitor which binds RIP3 kinase domain with high affinity (IC50=1.8 nM) and inhibits kinase activity with IC50 of 1.3 nM. It has minimal cross-reactivity.
| Trivial name | GSK2399872A |
| Catalog Number | S8465 |
| Molecular Formula | C19H17N3O2S2 |
| CAS# | 1346546-69-7 |
| Inchi | InChI=1S/C19H17N3O2S2/c1-12(2)26(23,24)14-4-5-16-15(10-14)17(7-8-20-16)22-13-3-6-19-18(9-13)21-11-25-19/h3-12H,1-2H3,(H,20,22) |
| Inchi Key | ZCDBTQNFAPKACC-UHFFFAOYSA-N |
| SMILES | CC(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=CC4=C(C=C3)SC=N4 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/GSK872-GSK2399872A.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk872-gsk2399872a-chemical-structure-s8465.gif |