JNJ-42165279
JNJ-42165279 covalently inactivates the FAAH enzyme but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 (10 μM) exhibits high selectivity against a panel of 50 receptors, enzymes, transporters, and ion-channels, at which concentration it does not produce >50% inhibition of binding to any of the targets. Fortunately, JNJ-42165279 (10 μM) also does not inhibit CYPs (1A2, 2C8, 2C9, 2C19, 2D6, 3A4) or hERG.

Catalog Number | T3215 |
Alternative Name(s) | JNJ42165279 |
Research Area | Metabolism|||Neuroscience|||Autophagy |
Molecular Formula | C18H17ClF2N4O3 |
CAS# | 1346528-50-4 |
Purity | 99.89% |
SMILES | C1CN(CCN1Cc1cc2c(cc1)OC(O2)(F)F)C(=O)Nc1c(ccnc1)Cl |
Size | 5 mg |
Supplier Page | https://www.targetmol.com/compound/JNJ-42165279 |
Additional Information | https://www.targetmol.com/datasheet/T3215 |