JNJ-42165279

JNJ-42165279 covalently inactivates the FAAH enzyme but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 (10 μM) exhibits high selectivity against a panel of 50 receptors, enzymes, transporters, and ion-channels, at which concentration it does not produce >50% inhibition of binding to any of the targets. Fortunately, JNJ-42165279 (10 μM) also does not inhibit CYPs (1A2, 2C8, 2C9, 2C19, 2D6, 3A4) or hERG.

Price Not Available 10 mg JNJ-42165279 Supplier Page
Catalog Number T3215
Alternative Name(s) JNJ42165279
Research Area Metabolism|||Neuroscience|||Autophagy
Molecular Formula C18H17ClF2N4O3
CAS# 1346528-50-4
Purity 99.89%
SMILES C1CN(CCN1Cc1cc2c(cc1)OC(O2)(F)F)C(=O)Nc1c(ccnc1)Cl
Size 10 mg
Supplier Page https://www.targetmol.com/compound/JNJ-42165279
Additional Information https://www.targetmol.com/datasheet/T3215