Erdafitinib
Erdafitinib is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Erdafitinib also binds to RET (c-RET), CSF-1R, PDGFR-α/PDGFR-β, FLT4, Kit (c-Kit) and VEGFR-2 and induces cellular apoptosis.
| Trivial name | JNJ-42756493 |
| Catalog Number | S8401 |
| Molecular Formula | C25H30N6O2 |
| CAS# | 1346242-81-6 |
| Inchi | InChI=1S/C25H30N6O2/c1-17(2)26-8-9-31(20-10-21(32-4)13-22(11-20)33-5)19-6-7-23-24(12-19)29-25(15-27-23)18-14-28-30(3)16-18/h6-7,10-17,26H,8-9H2,1-5H3 |
| Inchi Key | OLAHOMJCDNXHFI-UHFFFAOYSA-N |
| SMILES | CC(C)NCCN(C1=CC2=NC(=CN=C2C=C1)C3=CN(N=C3)C)C4=CC(=CC(=C4)OC)OC |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/jnj-42756493-erdafitinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/jnj-42756493-erdafitinib-chemical-structure-s8401.gif |