EGFR/HER2-IN-11 | MedChemExpress (MCE)
EGFR/HER2-IN-11 (compound 20) is an orally active dual inhibitor for human epidermal growth factor receptor 2 (HER2) and epidermal growth factor receptor (EGFR), with IC50s of 7.7 and 22 nM, respectively. EGFR/HER2-IN-11 exhibits antitumor efficacy and inhibits proliferation against cancer cells BT-474 with GI50 of 601 nM[1].
| Trivial name | EGFR/HER2-IN-11 |
| Catalog Number | HY-160613 |
| Research Area | Cancer |
| CAS# | 1346176-20-2 |
| Purity | ≥98.0% |
| SMILES | FC(F)(C1=CC(OC2=CC=C(NC3=NC=NC4=C3N(CCNCCO)C=C4)C=C2Cl)=CC=C1)F |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/egfr-her2-in-11.html |