RKI-1447
RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, has anti-invasive and antitumor activities.
| Trivial name | N/A |
| Catalog Number | S7195 |
| Molecular Formula | C16H14N4O2S |
| CAS# | 1342278-01-6 |
| Inchi | InChI=1S/C16H14N4O2S/c21-13-3-1-2-11(8-13)9-18-15(22)20-16-19-14(10-23-16)12-4-6-17-7-5-12/h1-8,10,21H,9H2,(H2,18,19,20,22) |
| Inchi Key | GDVRVPIXWXOKQO-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/rki-1447.html |
| Additional Information | https://file.selleck.cn/downloads/struct/RKI-1447-chemical-structure-s7195.gif |