Fimepinostat (CUDC-907)
CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. CUDC-907 induces cell cycle arrest and apoptosis in breast cancer cells. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2759 |
| Molecular Formula | C15H11NO3S2 |
| CAS# | 1339928-25-4 |
| Inchi | InChI=1S/C15H11NO3S2/c17-14-8-7-11-4-1-2-5-12(11)13(14)10-16-21(18,19)15-6-3-9-20-15/h1-10,17H/b16-10+ |
| Inchi Key | TVIVJHZHPKNDAQ-MHWRWJLKSA-N |
| SMILES | C1=CC=C2C(=C1)C=CC(=C2C=NS(=O)(=O)C3=CC=CS3)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/pi3k-hdac-inhibitor-i.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CUDC-907-chemical-structure-s2759.gif |
