OTS514
OTS514 is a highly potent TOPK inhibitor with an IC50 of 2.6 nM. OTS514 strongly suppresses the growth of TOPK-positive cancer cells. OTS514 induces cell cycle arrest and apoptosis.
| Catalog Number | E7590 |
| Molecular Formula | C20H21FN6O5 |
| CAS# | 1338540-63-8 |
| Inchi | InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30) |
| Inchi Key | CZFFBEXEKNGXKS-UHFFFAOYSA-N |
| SMILES | CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)O)C(=O)NCC3=CC=C(C=C3)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ots514-e7590.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7590-ots514-chemical-structure-tube.png |