Taminadenant
Taminadenant (NIR178, PBF509) is a non-xanthine and non-furan antagonist of adenosine A2A receptor (A2AR). It can antagonize A2AR agonist-mediated cAMP accumulation and impedance responses with Kb values of 72.8 nM and 8.2 nM, respectively. It exhibits potential utility for Parkinson’s disease (PD) treatment.
| Trivial name | NIR178, PBF509 |
| Catalog Number | E4632 |
| Molecular Formula | C24H20N4O3S |
| CAS# | 1337962-47-6 |
| SMILES | C1C2=CN(C(=O)C=C2NC(=O)N1C3=CC(=CC=C3)OCC4=CN=CS4)CC5=CC=CC=C5 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/taminadenant.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4632-Taminadenant-chemical-structure.png |