GSK2193874
GSK2193874 is an orally active, potent, and selective blocker of transient receptor potential vanilloid 4 (TRPV4) with IC50 values of 0.04 and 0.002 μM for hTRPV4 and rTRPV4, respectively.
| Trivial name | N/A |
| Catalog Number | S8367 |
| Molecular Formula | C37H38BrF3N4O |
| CAS# | 1336960-13-4 |
| Inchi | InChI=1S/C37H38BrF3N4O/c38-28-12-13-30-32(23-28)42-34(25-8-7-11-27(22-25)37(39,40)41)31(24-44-20-14-29(15-21-44)45-18-5-2-6-19-45)33(30)35(46)43-36(16-17-36)26-9-3-1-4-10-26/h1,3-4,7-13,22-23,29H,2,5- 6,14-21,24H2,(H,43,46) |
| Inchi Key | UIVOZBSCHXCGPS-UHFFFAOYSA-N |
| SMILES | C1CCN(CC1)C2CCN(CC2)CC3=C(C4=C(C=C(C=C4)Br)N=C3C5=CC(=CC=C5)C(F)(F)F)C(=O)NC6(CC6)C7=CC=CC=C7 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/gsk2193874.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk2193874-chemical-structure-S8367.gif |