MG132
MG132 ((S,R,S)-(-)-MG132, Z-Leu-D-Leu-Leu-al) is a potent proteasome (ChTL, TL, and PGPH) inhibitor. MG132 also inhibits calpain (IC50=1.2 μM). MG132 can be used to induce animal models of Parkinson’s disease.
| Trivial name | (S,R,S)-(-)-MG-132, Z-Leu-D-Leu-Leu-al |
| Catalog Number | S2619 |
| Molecular Formula | C13H10BrN3O4 |
| CAS# | 1211877-36-9 |
| Inchi | InChI=1S/C13H10BrN3O4/c14-9-3-1-2-4-10(9)15-13(19)16-11-6-5-8(17(20)21)7-12(11)18/h1-7,18H,(H2,15,16,19) |
| Inchi Key | MQBZVUNNWUIPMK-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/MG132.html |
| Additional Information | https://file.selleck.cn/downloads/struct/MG-132-chemical-structure-s2619.gif |