KPT-185
KPT-185 is a selective CRM1 inhibitor that induces growth inhibition and apoptosis in a panel of NHL cell lines with a median IC50 ~25 nM.
| Trivial name | N/A |
| Catalog Number | S7125 |
| Molecular Formula | C16H16F3N3O3 |
| CAS# | 1333151-73-7 |
| Inchi | InChI=1S/C16H16F3N3O3/c1-10(2)25-14(23)4-5-22-9-20-15(21-22)11-6-12(16(17,18)19)8-13(7-11)24-3/h4-10H,1-3H3/b5-4- |
| Inchi Key | NLNGWFLRRRYNIL-PLNGDYQASA-N |
| SMILES | CC(C)OC(=O)C=CN1C=NC(=N1)C2=CC(=CC(=C2)OC)C(F)(F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/kpt-185.html |
| Additional Information | https://file.selleck.cn/downloads/struct/KPT-185-chemical-structure-s7125.gif |