Bisindolylmaleimide I
GF109203X is a potent PKC inhibitor with IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ in cell-free assays, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor.
| Trivial name | GO 6850; Bisindolylmaleimide IGF109203X; GF 109203X |
| Catalog Number | CSN10464 |
| Alternative Name(s) | GO 6850; Bisindolylmaleimide IGF109203X; GF 109203X |
| Research Area | Metabolic Disease |
| Molecular Formula | C25H24N4O2 |
| CAS# | 133052-90-1 |
| Purity | ≥99% |
| SMILES | O=C(N1)C(C2=CN(CCCN(C)C)C3=C2C=CC=C3)=C(C4=CNC5=C4C=CC=C5)C1=O |
| Size | 1mg |
| Supplier Page | https://www.csnpharm.com/products/bisindolylmaleimide-i.html |