Iberdomide (CC220)
Iberdomide (CC-220) is a novel oral immunomodulatory compound that targets cereblon, part of the CRL4CRBN E3 ubiquitin ligase complex, with an IC50 of 60 nM in a competitive TR-FRET assay. Iberdomide (CC-220) induces apoptosis with antitumor and immunostimulatory activities.
| Trivial name | N/A |
| Catalog Number | S8760 |
| Molecular Formula | C25H27N3O5 |
| CAS# | 1323403-33-3 |
| Inchi | InChI=1S/C25H27N3O5/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27/h1-7,21H,8-16H2,(H,26,29,30)/t21-/m0/s1 |
| Inchi Key | IXZOHGPZAQLIBH-NRFANRHFSA-N |
| SMILES | C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3OCC4=CC=C(C=C4)CN5CCOCC5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/iberdomide.html |
| Additional Information | https://file.selleck.cn/downloads/struct/iberdomide-cc220-chemical-structure-s8760.gif |