Citarinostat (ACY-241)
Citarinostat (ACY-241, HDAC-IN-2) is an orally available selective HDAC6 inhibitor with IC50 of 2.6 nM and 46 nM for HDAC6 and HDAC3, respectively. It has 13 to 18-fold selectivity towards HDAC6 in comparison to HDAC1-3.
| Trivial name | HDAC-IN-2 |
| Catalog Number | S8464 |
| Molecular Formula | C24H26ClN5O3 |
| CAS# | 1316215-12-9 |
| Inchi | InChI=1S/C24H26ClN5O3/c25-20-12-7-8-13-21(20)30(19-10-4-3-5-11-19)24-27-16-18(17-28-24)23(32)26-15-9-2-1-6-14-22(31)29-33/h3-5,7-8,10-13,16-17,33H,1-2,6,9,14-15H2,(H,26,32)(H,29,31) |
| Inchi Key | VLIUIBXPEDFJRF-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)N(C2=CC=CC=C2Cl)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)NO |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/citarinostat-acy-241.html |
| Additional Information | https://file.selleck.cn/downloads/struct/citarinostat-acy-241-chemical-structure-S8464.gif |