PDZ1 Domain inhibitor peptide
A cyclic peptide that disrupts interaction between GluK2 (formally GluR6) and postsynaptic density protein 95 (PSD-95) through competing with the C terminal of GluK2 to bind the PDZ1 domain of PSD-95. It inhibits clustering of kainate receptors.
| Catalog Number | R0842 |
| Molecular Formula | C38H61N9O11 |
| CAS# | 1315378-73-4 |
| Purity | >98% |
| Inchi | InChI=1S/C38H61N9O11/c1-20(2)30(38(57)58)46-32(51)21(3)42-34(53)28-15-16-29(50)41-18-8-6-10-27(36(55)47-31(22(4)48)37(56)45-28)44-35(54)26(9-5-7-17-39)43-33(52)25(40)19-23-11-13-24(49)14-12-23/h11-14,20-22,25-28,30-31,48-49H,5-10,15-19,39-40H2,1-4H3,(H,41,50)(H,42,53)(H,43,52)(H,44,54)(H,45,56)(H,46,51)(H,47,55)(H,57,58)/t21-,22+,25-,26-,27-,28-,30-,31-/m0/s1 |
| Inchi Key | XXRRADBJCXMGOW-RMLJCASOSA-N |
| SMILES | C[C@H]([C@H]1C(=O)N[C@@H](CCC(=O)NCCCC[C@@H](C(=O)N1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O)O |
| Size | Inquiry |
| Supplier Page | https://www.creative-peptides.com/product/pdz1-domain-inhibitor-peptide-item-r0842-34644.html |