H 89 2HCl
H 89 2HCl is a potent PKA inhibitor with Ki of 48 nM in a cell-free assay, 10-fold selective for PKA than PKG,500-fold greater selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II. H 89 2HCl induces autophagy.
| Trivial name | N/A |
| Catalog Number | S1582 |
| Molecular Formula | C20H20BrN3O2S.2HCl |
| CAS# | 130964-39-5 |
| Inchi | InChI=1S/C20H20BrN3O2S.2ClH/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20;;/h1-10,12,15,22,24H,11,13-14H2;2*1H/b3-2+;; |
| Inchi Key | GELOGQJVGPIKAM-WTVBWJGASA-N |
| SMILES | C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNCC=CC3=CC=C(C=C3)Br.Cl.Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/H-89-dihydrochloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/H-89-dihydrochloride-chemical-structure-S1582.gif |