Entacapone
Entacapone (OR-611) inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. Entacapone can be used for the research of Parkinson’s disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.
| Trivial name | OR-611 |
| Catalog Number | S3147 |
| Molecular Formula | C14H15N3O5 |
| CAS# | 130929-57-6 |
| Inchi | InChI=1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+ |
| Inchi Key | JRURYQJSLYLRLN-BJMVGYQFSA-N |
| SMILES | CCN(CC)C(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C#N |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/entacapone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Entacapone-chemical-structure-s3147.gif |