Sulfatinib
Sulfatinib is a potent and highly selective tyrosine kinase inhibitor against VEGFR1, VEGFR2, VEGFR3, FGFR1 and CSF1R with IC50 of 2 nM, 24 nM, 1 nM, 15 nM and 4 nM, respectively. Sulfatinib shows encouraging antitumor activity and manageable toxicities in patients with advanced NETs.
| Trivial name | HMPL-012, Surufatinib |
| Catalog Number | S0487 |
| Molecular Formula | C24H28N6O3S |
| CAS# | 1308672-74-3 |
| SMILES | CC1=CC2=C(N1)C=CC(=C2)OC3=NC(=NC=C3)NC4=CC=CC(=C4)CS(=O)(=O)NCCN(C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sulfatinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0487-sulfatinib-chemical-structure.gif |