Y-27632, Dihydrochloride
Selective inhibitor of the Rho-associated protein kinase p160ROCK. Ki values are 0.14, 26, 25 and >250 µM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase, respectively. Prevents apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem cells (hES) without affecting their pluripotency.
| Catalog Number | ABS-075 |
| Alternative Name(s) | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecar boxamide dihydrochloride |
| CAS# | 129830-38-2 |
| Inchi | InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1 |
| Inchi Key | IDDDVXIUIXWAGJ-DDSAHXNVSA-N |
| SMILES | CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/y-27632-dihydrochloride-item-1539.html |