Romidepsin
Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.
Trivial name | FK228, Depsipeptide, FR 901228, NSC 630176, |
Catalog Number | S3020 |
Molecular Formula | C19H16N2O2 |
CAS# | 128517-07-7 |
Inchi | InChI=1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2 |
Inchi Key | OQQVFCKUDYMWGV-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)C4=CC=C(O4)CO |
Size | 1mg |
Supplier Page | http://www.selleckchem.com/products/Romidepsin-FK228.html |
Additional Information | https://file.selleck.cn/downloads/struct/romidepsin-FK228-chemical-structure-s3020.gif |