Romidepsin
Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.
| Trivial name | FK228, Depsipeptide, FR 901228, NSC 630176, |
| Catalog Number | S3020 |
| Molecular Formula | C24H36N4O6S2 |
| CAS# | 128517-07-7 |
| Inchi | InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28, 30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1 |
| Inchi Key | OHRURASPPZQGQM-GCCNXGTGSA-N |
| SMILES | CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Romidepsin-FK228.html |
| Additional Information | https://file.selleck.cn/downloads/struct/romidepsin-FK228-chemical-structure-s3020.gif |