FK228

A natural prodrug that inhibits Class I histone deacetylases (HDACs) (IC50 values are: 36, 47, 510 and 14000 nM for HDAC1, HDAC2, HDAC4 and HDAC6, respectively). Displays potent anticancer activities.

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Catalog Number	ABH-008
Alternative Name(s)	Romidepsin; Depsipeptide; FR901228
CAS#	128517-07-7
Inchi	InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1
Inchi Key	OHRURASPPZQGQM-GCCNXGTGSA-N
SMILES	CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C
Size	Inquiry
Supplier Page	https://www.agingclocks.com/fk228-item-1423.html