CU-CPT 4a
CU-CPT 4a (TLR3-IN-1) is a potent small molecule antagonist of TLR3 with an IC50 of 3.44 µM that also inhibits TLR3/dsRNA-mediated signaling, including TNF-α and IL-1β expression. It is a valuable tool for studying protein-RNA complexes.
| Trivial name | TLR3-IN-1 |
| Catalog Number | E5778 |
| Molecular Formula | C17H14F3N3O2S |
| CAS# | 1279713-77-7 |
| Inchi | InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) |
| Inchi Key | RZEKVGVHFLEQIL-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/cu-cpt-4a.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5778-CU-CPT-4a-chemical-structure.png |