Varoglutamstat
Varoglutamstat (PQ912) is an inhibitor of glutaminyl cyclase (QC), inhibiting human glutaminyl cyclase (hQC) activity with a Ki of 25 nM (pH 8.0). It reduces pyroglutamyl-Aβ (pE-Aβ) levels and can be used in Alzheimer’s disease research.
| Trivial name | PQ912 |
| Catalog Number | S0792 |
| Molecular Formula | C19H22ClN5O |
| CAS# | 1276021-65-8 |
| Inchi | InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2 |
| Inchi Key | PHLBKPHSAVXXEF-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pq912.html |
| Additional Information | https://file.selleck.cn/downloads/struct/S0792-Varoglutamstat-chemical-structure.png |