Sivelestat
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM. It almost shows no activity at a range of other proteases.
| Trivial name | ONO-5046, LY544349, EI546 |
| Catalog Number | S8136 |
| Molecular Formula | C20H22N2O7S |
| CAS# | 127373-66-4 |
| Inchi | InChI=1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24) |
| Inchi Key | BTGNGJJLZOIYID-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/sivelestat-ono-5046.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sivelestat-ono-5046-chemical-structure-s8136.gif |