BMS-911543
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.
| Catalog Number | S7144 |
| Molecular Formula | C23H28N8O |
| CAS# | 1271022-90-2 |
| Inchi | InChI=1S/C23H28N8O/c1-5-30-17(23(32)31(14-6-7-14)15-8-9-15)11-16-20-19(24-12-28(20)3)21(26-22(16)30)25-18-10-13(2)29(4)27-18/h10-12,14-15H,5-9H2,1-4H3,(H,25,26,27) |
| Inchi Key | JCINBYQJBYJGDM-UHFFFAOYSA-N |
| SMILES | CCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/bms-911543.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BMS-911543-chemical-structure-s7144.gif |