Zoligratinib (Debio-1347)

Zoligratinib (Debio-1347, CH5183284, FF284) is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1.

Trivial name CH5183284, FF284
Catalog Number S7665
Molecular Formula C20H16N6O
CAS# 1265229-25-1
Inchi InChI=1S/C20H16N6O/c1-11-23-16-7-6-13(9-17(16)24-11)26-20(21)14(10-22-26)19(27)18-8-12-4-2-3-5-15(12)25-18/h2-10,25H,21H2,1H3,(H,23,24)
Inchi Key BEMNJULZEQTDJY-UHFFFAOYSA-N
SMILES CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N
Size 1g
Supplier Page http://www.selleckchem.com/products/ch5183284-debio-1347.html
Additional Information https://file.selleck.cn/downloads/struct/ch5183284-debio-1347-chemical-structure-s7665.gif