NMS-P118
NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively).
| Trivial name | N/A |
| Catalog Number | S8363 |
| Molecular Formula | C20H24F3N3O2 |
| CAS# | 1262417-51-5 |
| Inchi | InChI=1S/C20H24F3N3O2/c21-13-9-12-11-26(19(28)17(12)16(10-13)18(24)27)15-3-7-25(8-4-15)14-1-5-20(22,23)6-2-14/h9-10,14-15H,1-8,11H2,(H2,24,27) |
| Inchi Key | ARYVAQSYRLZVQD-UHFFFAOYSA-N |
| SMILES | C1CC(CCC1N2CCC(CC2)N3CC4=C(C3=O)C(=CC(=C4)F)C(=O)N)(F)F |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/nms-p118.html |
| Additional Information | https://file.selleck.cn/downloads/struct/nms-p118-chemical-structure-S8363.gif |