Molibresib (I-BET-762)

Molibresib (I-BET-762, GSK525762, GSK525762A) is an inhibitor for BET proteins with IC50 of ~35 nM in a cell-free assay, suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation, highly selective over other bromodomain-containing proteins.

Price Not Available 1g Molibresib (I-BET-762) Supplier Page

Trivial name	GSK525762, GSK525762A
Catalog Number	S7189
Molecular Formula	C22H22ClN5O2
CAS#	1260907-17-2
Inchi	InChI=1S/C22H22ClN5O2/c1-4-24-20(29)12-18-22-27-26-13(2)28(22)19-10-9-16(30-3)11-17(19)21(25-18)14-5-7-15(23)8-6-14/h5-11,18H,4,12H2,1-3H3,(H,24,29)/t18-/m0/s1
Inchi Key	AAAQFGUYHFJNHI-SFHVURJKSA-N
SMILES	CCNC(=O)CC1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C
Size	1g
Supplier Page	http://www.selleckchem.com/products/i-bet-762.html
Additional Information	https://file.selleck.cn/downloads/struct/GSK525762-I-BET-762-chemical-structure-s7189.gif