Vonoprazan Fumarate (TAK-438)
Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Phase 3.
Trivial name | N/A |
Catalog Number | S8016 |
Molecular Formula | C17H16FN3O2S.C4H4O4 |
CAS# | 1260141-27-2 |
Inchi | InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+ |
Inchi Key | ROGSHYHKHPCCJW-WLHGVMLRSA-N |
SMILES | CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=CC(=O)O)C(=O)O |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/tak-438.html |
Additional Information | https://file.selleck.cn/downloads/struct/TAK-438-chemical-structure-s8016.gif |