Sarsasapogenin
Sarsasapogenin (SAR, Parigenin) is a steroidal sapogenin. It can provoke the generation of reactive oxygen species and activate unfolded protein response (UPR) signaling pathways. SAR potently inhibits NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages.
| Trivial name | Parigenin |
| Catalog Number | S3607 |
| Molecular Formula | C21H22N4O2 |
| CAS# | 126-19-2 |
| Inchi | InChI=1S/C21H22N4O2/c1-13(26)14-8-10-16(11-9-14)24-25-19(20(22)27)18-17-7-5-4-6-15(17)12-21(2,3)23-18/h4-11,23H,12H2,1-3H3,(H2,22,27)/b19-18+,25-24+ |
| Inchi Key | ZXSRRUROLCGTBS-KEYVSXKFSA-N |
| SMILES | CC(=O)C1=CC=C(C=C1)NN=C(C2=NC(CC3=CC=CC=C32)(C)C)C(=O)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sarsasapogenin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sarsasapogenin-chemical-structure-s3607.gif |