Sarsasapogenin
Sarsasapogenin (SAR, Parigenin) is a steroidal sapogenin. It can provoke the generation of reactive oxygen species and activate unfolded protein response (UPR) signaling pathways. SAR potently inhibits NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages.
| Trivial name | Parigenin |
| Catalog Number | S3607 |
| Molecular Formula | C17H9Cl2N3O2 |
| CAS# | 126-19-2 |
| Inchi | InChI=1S/C17H9Cl2N3O2/c18-9-5-6-10(13(19)7-9)15(23)12(8-20)16-21-14-4-2-1-3-11(14)17(24)22-16/h1-7,21H,(H,22,24)/b16-12+ |
| Inchi Key | SESYPWCSIZUIAS-FOWTUZBSSA-N |
| SMILES | C1=CC=C2C(=C1)C(=O)NC(=N2)C(=C(C3=C(C=C(C=C3)Cl)Cl)O)C#N |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sarsasapogenin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sarsasapogenin-chemical-structure-s3607.gif |