BMS-986020
BMS-986020 (AM152, AP-3152 free acid) is a potent and selective antagonist of lysophosphatidic acid receptor 1 (LPA1). BMS-986020 inhibits bile acid and phospholipid transporters with IC50 of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).
| Trivial name | AM152, AP-3152 free acid |
| Catalog Number | S3572 |
| Molecular Formula | C29H26N2O5 |
| CAS# | 1257213-50-5 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CC(OC(=O)NC1=C(ON=C1C)C2=CC=C(C=C2)C3=CC=C(C=C3)C4(CC4)C(O)=O)C5=CC=CC=C5 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/bms-986020.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s3572-bms-986020-chemical-structure.gif |