Alectinib
Alectinib is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429.
| Trivial name | AF-802, RG-7853,CH5424802 |
| Catalog Number | S2762 |
| Molecular Formula | C34H33N3O5 |
| CAS# | 1256580-46-7 |
| Inchi | InChI=1S/C34H33N3O5/c1-40-28-9-5-7-26-32(28)36-31-25(33(26)38)6-4-8-27(31)34(39)35-24-12-10-21(11-13-24)14-16-37-17-15-22-18-29(41-2)30(42-3)19-23(22)20-37/h4-13,18-19H,14-17,20H2,1-3H3,(H,35,39)(H,36 ,38) |
| Inchi Key | OSFCMRGOZNQUSW-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC2=C1NC3=C(C2=O)C=CC=C3C(=O)NC4=CC=C(C=C4)CCN5CCC6=CC(=C(C=C6C5)OC)OC |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/ch5424802.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CH5424802-chemical-structure-s2762.gif |