Alectinib
Alectinib is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429.
| Trivial name | AF-802, RG-7853,CH5424802 |
| Catalog Number | S2762 |
| Molecular Formula | C30H34N4O2 |
| CAS# | 1256580-46-7 |
| Inchi | InChI=1S/C30H34N4O2/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29/h5-6,15-17,21,32H,4,7-14H2,1-3H3 |
| Inchi Key | KDGFLJKFZUIJMX-UHFFFAOYSA-N |
| SMILES | CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/ch5424802.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CH5424802-chemical-structure-s2762.gif |