XL388
XL388 is a highly potent, selective, ATP-competitive inhibitor of mTOR with IC50 of 9.9 nM, 1000-fold selectivity over the closely related PI3K kinases.
Trivial name | N/A |
Catalog Number | S7035 |
Molecular Formula | C23H22FN3O4S |
CAS# | 1251156-08-7 |
Inchi | InChI=1S/C23H22FN3O4S/c1-14-18(5-7-20(22(14)24)32(2,29)30)23(28)27-9-10-31-19-6-3-15(11-17(19)13-27)16-4-8-21(25)26-12-16/h3-8,11-12H,9-10,13H2,1-2H3,(H2,25,26) |
Inchi Key | LNFBAYSBVQBKFR-UHFFFAOYSA-N |
SMILES | CC1=C(C=CC(=C1F)S(=O)(=O)C)C(=O)N2CCOC3=C(C2)C=C(C=C3)C4=CN=C(C=C4)N |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/xl388.html |
Additional Information | https://file.selleck.cn/downloads/struct/XL388-chemical-structure-s7035.gif |