LGK-974
LGK-974 (NVP-LGK974, WNT974) is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells. Phase 1.
| Trivial name | NVP-LGK974, WNT974 |
| Catalog Number | S7143 |
| Molecular Formula | C23H20N6O |
| CAS# | 1243244-14-5 |
| Inchi | InChI=1S/C23H20N6O/c1-15-9-17(12-28-23(15)18-5-6-25-16(2)10-18)11-22(30)29-21-4-3-19(13-27-21)20-14-24-7-8-26-20/h3-10,12-14H,11H2,1-2H3,(H,27,29,30) |
| Inchi Key | XXYGTCZJJLTAGH-UHFFFAOYSA-N |
| SMILES | CC1=CC(=CN=C1C2=CC(=NC=C2)C)CC(=O)NC3=NC=C(C=C3)C4=NC=CN=C4 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/lgk-974.html |
| Additional Information | https://file.selleck.cn/downloads/struct/LGK-974-chemical-structure-s7143.gif |