Ixazomib Citrate

Ixabepilone is an anticancer drug.

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Catalog Number API0232851
Alternative Name(s) Ixazomib citrate; 1239908-20-3; NINLARO
Research Area API
Molecular Formula C20H23BCl2N2O9
CAS# 1239908-20-3
Inchi InChI=1S/C20H23BCl2N2O9/c1-10(2)5-14(21-33-19(32)20(34-21,7-16(27)28)8-17(29)30)25-15(26)9-24-18(31)12-6-11(22)3-4-13(12)23/h3-4,6,10,14H,5,7-9H2,1-2H3,(H,24,31)(H,25,26)(H,27,28)(H,29,30)/t14-/m0/s1
Inchi Key MBOMYENWWXQSNW-AWEZNQCLSA-N
SMILES B1(OC(=O)C(O1)(CC(=O)O)CC(=O)O)[C@H](CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl
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Ixazomib Citrate

Ixazomib inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome, which results in an accumulation of unwanted or misfolded proteins; disruption of various cell signaling pathways may follow, resulting in the induction of apoptosis.

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Catalog Number API1239908203
Alternative Name(s) NINLARO Ixazomib citrate (Ester) Ixazomib citrate [USAN]
Research Area Anti-Tumor APIs
Molecular Formula C20H23BCl2N2O9
CAS# 1239908-20-3
SMILES B1(OC(=O)C(O1)(CC(=O)O)CC(=O)O)C(CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl
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