SGI-7079
SGI-7079, a novel selective Axl inhibitor with an IC50 of 58 nM in vitro, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance.
| Trivial name | N/A |
| Catalog Number | S7847 |
| Molecular Formula | C26H26FN7 |
| CAS# | 1239875-86-5 |
| Inchi | InChI=1S/C26H26FN7/c1-17-16-29-25-23(17)24(19-5-3-4-18(14-19)8-9-28)31-26(32-25)30-20-6-7-22(21(27)15-20)34-12-10-33(2)11-13-34/h3-7,14-16H,8,10-13H2,1-2H3,(H2,29,30,31,32) |
| Inchi Key | BCFKACXAIBEPKR-UHFFFAOYSA-N |
| SMILES | CC1=CNC2=NC(=NC(=C12)C3=CC=CC(=C3)CC#N)NC4=CC(=C(C=C4)N5CCN(CC5)C)F |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sgi-7079.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sgi-7079-chemical-structure-s7847.gif |