Pimasertib (AS-703026)

Pimasertib (AS-703026, MSC1936369B, SAR 245509) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 2.

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Trivial name	MSC1936369B, SAR 245509
Catalog Number	S1475
Molecular Formula	C20H18N2O2
CAS#	1236699-92-5
Inchi	InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3
Inchi Key	VOFUROIFQGPCGE-UHFFFAOYSA-N
SMILES	CCN(CC)C1=CC2=C(C=C1)N=C3C4=CC=CC=C4C(=O)C=C3O2
Size	5mg
Supplier Page	http://www.selleckchem.com/products/AS703026.html
Additional Information	https://file.selleck.cn/downloads/struct/AS-703026-chemical-structure-S1475.gif