Pimasertib (AS-703026)

Pimasertib (AS-703026, MSC1936369B, SAR 245509) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 2.

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Trivial name	MSC1936369B, SAR 245509
Catalog Number	S1475
Molecular Formula	C15H15FIN3O3
CAS#	1236699-92-5
Inchi	InChI=1S/C15H15FIN3O3/c16-12-5-9(17)1-2-13(12)20-14-7-18-4-3-11(14)15(23)19-6-10(22)8-21/h1-5,7,10,20-22H,6,8H2,(H,19,23)/t10-/m0/s1
Inchi Key	VIUAUNHCRHHYNE-JTQLQIEISA-N
SMILES	C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NCC(CO)O
Size	1g
Supplier Page	http://www.selleckchem.com/products/AS703026.html
Additional Information	https://file.selleck.cn/downloads/struct/AS-703026-chemical-structure-S1475.gif