Prexasertib (LY2606368)
Prexasertib (LY2606368, ACR 368) is a selective ATP competitor inhibitor of Chk1 and Chk2 with IC50s of 1 nM and 8 nM in cell-free assays, respectively. Prexasertib also inhibits RSK1 with an IC50 of 9 nM in cell-free assay.
Trivial name | ACR 368 |
Catalog Number | S6385 |
Molecular Formula | C18H19N7O2 |
CAS# | 1234015-52-1 |
Inchi | #N/A |
Inchi Key | #N/A |
SMILES | COC1=C(C2=CC(=N[NH]2)NC3=CN=C(C=N3)C#N)C(=CC=C1)OCCCN |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/prexasertib-ly2606368.html |
Additional Information | https://file.selleck.cn/downloads/struct/s6385-prexasertib-ly2606368-chemical-structure.gif |