Clofarabine
Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.
| Trivial name | Clolar |
| Catalog Number | S1218 |
| Molecular Formula | C10H11ClFN5O3 |
| CAS# | 123318-82-1 |
| Inchi | InChI=1S/C10H11ClFN5O3/c11-10-15-7(13)5-8(16-10)17(2-14-5)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4+,6-,9-/m1/s1 |
| Inchi Key | WDDPHFBMKLOVOX-AYQXTPAHSA-N |
| SMILES | C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)F)Cl)N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Clofarabine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Clofarabine-chemical-structure-S1218.gif |