FRAX486
FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
Trivial name | N/A |
Catalog Number | S7807 |
Molecular Formula | C25H23Cl2FN6O |
CAS# | 1232030-35-1 |
Inchi | InChI=1S/C25H23Cl2FN6O/c1-2-34-23-15(11-19(24(34)35)18-5-3-16(26)12-20(18)27)14-30-25(32-23)31-17-4-6-22(21(28)13-17)33-9-7-29-8-10-33/h3-6,11-14,29H,2,7-10H2,1H3,(H,30,31,32) |
Inchi Key | DHKFOIHIUYFSOF-UHFFFAOYSA-N |
SMILES | CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)Cl)Cl)NC4=CC(=C(C=C4)N5CCNCC5)F |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/frax486.html |
Additional Information | https://file.selleck.cn/downloads/struct/frax486-chemical-structure-s7807.gif |