Abemaciclib
Abemaciclib is a cell cycle inhibitor selective for CDK4/6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively.
| Trivial name | LY2835219 |
| Catalog Number | S5716 |
| Molecular Formula | C27H32F2N8 |
| CAS# | 1231929-97-7 |
| Inchi | InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34) |
| Inchi Key | UZWDCWONPYILKI-UHFFFAOYSA-N |
| SMILES | CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/abemaciclib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/abemaciclib-chemical-structure-s5716.gif |