BMS-935177
BMS-935177 is a potent, reversible Bruton’s Tyrosine Kinase (BTK) inhibitor with an IC50 value of 2.8 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective.
| Trivial name | N/A |
| Catalog Number | S8348 |
| Molecular Formula | C31H26N4O3 |
| CAS# | 1231889-53-4 |
| Inchi | InChI=1S/C31H26N4O3/c1-17-19(8-6-10-26(17)35-16-33-24-9-5-4-7-22(24)30(35)37)20-13-14-23(29(32)36)28-27(20)21-12-11-18(31(2,3)38)15-25(21)34-28/h4-16,34,38H,1-3H3,(H2,32,36) |
| Inchi Key | TVJRDCQUZMGBAB-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC=C1N2C=NC3=CC=CC=C3C2=O)C4=C5C6=C(C=C(C=C6)C(C)(C)O)NC5=C(C=C4)C(=O)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/bms-935177.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bms-935177-chemical-structure-s8348.gif |