Gandotinib (LY2784544)
Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2179 |
| Molecular Formula | C25H30N6O |
| CAS# | 1229236-86-5 |
| Inchi | InChI=1S/C25H30N6O/c1-2-31-22-7-4-3-6-20(22)21-18-19(8-9-23(21)31)28-24-10-12-27-25(29-24)26-11-5-13-30-14-16-32-17-15-30/h3-4,6-10,12,18H,2,5,11,13-17H2,1H3,(H2,26,27,28,29) |
| Inchi Key | AFTZZRFCMOAFCR-UHFFFAOYSA-N |
| SMILES | CCN1C2=C(C=C(C=C2)NC3=NC(=NC=C3)NCCCN4CCOCC4)C5=CC=CC=C51 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/LY2784544.html |
| Additional Information | https://file.selleck.cn/downloads/struct/LY2784544-chemical-structure-S2179.gif |