Entospletinib (GS-9973)

Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13- to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.

Price Not Available 1g Entospletinib (GS-9973) Supplier Page

Trivial name	N/A
Catalog Number	S7523
Molecular Formula	C23H21N7O
CAS#	1229208-44-9
Inchi	InChI=1S/C23H21N7O/c1-2-17-14-25-28-20(17)13-16(1)21-15-30-8-7-24-23(30)22(27-21)26-18-3-5-19(6-4-18)29-9-11-31-12-10-29/h1-8,13-15H,9-12H2,(H,25,28)(H,26,27)
Inchi Key	XSMSNFMDVXXHGJ-UHFFFAOYSA-N
SMILES	C1COCCN1C2=CC=C(C=C2)NC3=NC(=CN4C3=NC=C4)C5=CC6=C(C=C5)C=NN6
Size	1g
Supplier Page	http://www.selleckchem.com/products/gs-9973.html
Additional Information	https://file.selleck.cn/downloads/struct/GS-9973-chemical-structure-s7523.gif