Onatasertib
CC-223 is an orally available mTOR inhibitor with potential antitumor activity. CC-223 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. CC-223 is a potent mTOR kinase inhibitor (IC50: 16 nM), with >150-fold sensitivity than the related lipid kinase PI3Kα (IC50: 4 μM).
| Catalog Number | T3351 |
| Alternative Name(s) | CC223 , CC 223 , CC-223 |
| Research Area | PI3K/Akt/mTOR signaling|||Apoptosis|||DNA Damage/DNA Repair|||Tyrosine Kinase/Adaptors|||Angiogenesis |
| Molecular Formula | C21H27N5O3 |
| CAS# | 1228013-30-6 |
| Purity | 99.41% |
| SMILES | CO[C@H]1CC[C@@H](CC1)N1C(=O)CNc2ncc(nc12)-c1ccc(nc1)C(C)(C)O |
| Size | 5 mg |
| Supplier Page | https://www.targetmol.com/compound/Onatasertib |
| Additional Information | https://www.targetmol.com/datasheet/T3351 |